Dubya_B Lab Results

[Dubbya_B]

My labwork:
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7/22/2011 at 8:40 am.


I had not taken any drugs or supplements that have any hormonal effects for over 6 months.


Inhibin-A was tested instead of Inhibin-B. This was a mistake. Inhibin-B was supposed to be tested because it inhibits FSH secretion.

ACTH: 31 (7-50)pg/ml

Prolactin: 14.1 (2.8-29.9)ng/ml

LH: 2.8 (2.0-9.0)mIU/ml

FSH: 0.7 (0.9-15.0)mIU/ml L

Inhibin-A: 1 (<21)pg/ml

Cortisol: 20.4 (9-25)ug/dl

DHEAS: 523 (110-370)ug/dl H

17 OH-Progesterone: 90 (32-307)ng/dl

IGF-1: 207 (53-331)ng/ml Z-score = 0.7 (-2.0 to +2.0)

Total T: 729 (250-1100)ng/dl

Free T: 168.4 (35-155)pg/ml H

DHT: 63 (25-75)ng/dl

E2: 17 (6-54)pg/ml

Adiol-G: 315 (260-1500)ng/dl



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10/01/2010

8:30 AM

tests performed by Quest

DHEA Sulfate - 736 range: 110-510 (H)

IGF-1, ECL - 333 range: 88-374

Cortisol - 20.3 range: 4.0-22.0



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8/30/2010

Labs 3 weeks into treatment with Tamoxifen 10mg SR daily.

9:06 AM

tests performed by Quest


Testosterone - 640 range: 250-1100

% Free T - 2.59 range: 1.50-2.20 (H)

Free T - 165.8 range: 35.0-155.0 (H)

SHBG - 21 range: 7-49

Estradiol - 35 range: 13-54

DHT - 53 range: 25-75

Cortisol - 26.1 range: 4.0-22.0 (H)



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7/22/2010

Labs for Clomiphene Stimulation Test (Took 25mg Clomiphene daily for one week before blood draw)

10:20 AM

tests performed by Quest Diagnostics



Testosterone - 855 range: 241-827 (H)

Estradiol - 50 range: 13-54

DHT - 33 range: 25-75

Vitamin D - 43 range: 30-100

Prolactin - 8.2 range: 2-18

FSH - 2.2 range: 1.6-8.0

LH - 6.4 range: 1.5-9.3



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6/18/2003

2:30 PM

tests performed by quest

(I do not have ref ranges for these tests)


Testosterone - 535 ng/dl

% Free T - 2.39

Free T - 128.0


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2002

Had pituitary MRI (sequential slice method) to look for possible adenoma as cause for low FSH levels. No abnormalities were found.

 

[Dubbya_B]

February and March 2010

 

[Dubbya_B]

Semen Analysis in May 2010 had many aberrations with borderline low fertility




Testicular Ultrasound from April 2010 was normal

 

[Dubbya_B]

Rhein 24 Hour Urinary Steroid Assay (shows low 5-alpha reduced cortisol metabolite 5a-THF)





24hr Rheins urine analysis provides measurements of THF (tetrahydrocortisol) and 5a-THF (allo-tetrahydrocortisol), and the ratio of 5a-THF to THF ( ie: 5a-THF / THF ) follows the 5alpha reductase activity, ie:

high ( 5a-THF / THF > 1.3 ) shows high 5 alpha reductase activity (above 90 percentile)

mid ( 5a-THF / THF = 0.8 ) shows average 5 alpha reductase activity

low ( 5a-THF / THF < 0.6) shows low 5 alpha reductase activity (below 10 percentile)


My 5a-THF / THF ratio was 0.4 (below 10th percentile)


"Evidence for decreased androgen 5 alpha-reduction in skin and liver of men with severe acne after 13-cis-retinoic acid treatment." - Boudou 1994, describes a decrease in the mean androsterone/etiocholanolone ratio from 1.70 (SD = 0.35) pre-treatment, to 1.10 (SD = 0.10) post-treatment, indicative of a "metabolic deviation from the 5-alpha to 5-beta-reduction pathway in the liver"

My androsterone/etiocholanolone ratio was 0.7 (10 standard deviations below post-treatment mean)





June 2010 Basic Bloodwork

 

[Dubbya_B]

Some older stuff from early 2000s. Low FSH is a common theme.

 

[flynn]

Thanks for posting. This is pretty extensive lab work. Its interesting that your FSH is low, this may also account for the low fertility you reported.

 

[Alex Jaramillo]

What kind of dietary changes did you make? I ask because your T/DHT went up over time

 

[Dubbya_B]

No dietary changes during the 3 times I had DHT tested. I was eating on the healthier side with a meat (beef, pork, fish, chicken) carb (rice or potatoes) and veggie for dinner. Would have leftovers from dinner for lunch the next day. Usually had a doughnut or sausage muffin for breakfast. Very little junk food. I might eat a bowel of chips or popcorn a few hours after dinner.

I ate like crap in my early 20s (pizza and burgers and fries) and my T went up.

I don't believe this problem can be fixed with special diets. Maybe there are some diets that can help those with gastrointestinal side effects, but not those like me.

Probably best to eat healthy in general and exercise.